Functions

Boron is distributed throughout the body with the highest concentrations in bone and dental enamel. It appears to function for bone and joint health, possible due to effects on calcium, magnesium and phosphorus metabolism. It also seems to be involved in cell membrane signalling. Boron affects steroid hormone metabolism and may help convert vitamin D to a more active form to encourage calcium uptake.

Uses

Osteoporosis, osteoarthritis, fungal infections

Deficiency

Deficiency may affect bone composition leading to osteoporotic-like changes probably due to effects on calcium and other bone minerals.

Antagonists

Contraindicated during dialysis - can lead to neurological sx. Food processing techniques can destroy biotin. Raw egg white contains a protein called avidin that prevents biotin absorption.

Co-factors

Works with calcium, magnesium, phosphorus, vitamin D.

Drug Interactions

None known.

Dose

No RDA. Safe dose considered to be between 1 and 10 mg.

Toxicity

Toxic effects appear at intakes of about 100 mg. The World Health Organization has banned boron (in the form of boric acid) as a food additive and preservative. Toxic effects include a red rash with weeping skin, vomiting, diarrhea characterized by a blue green color, depressed blood circulation, coma and convulsions. A fatal dose in adults is 15 to 20 g andin children 3 to 6 g. Repeated intakes of small amounts can cause accumulative toxicity.

Sources

Fruit, vegetables, soybeans and nuts are rich sources but levels do depend on soil boron. Wine, cider and beer contain significant amounts.